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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10908f26566cef1edb42fccedc89f17e19ab635fda5299d0362a52342a8eeed3' 
  AND token = 'u81b6T4gnNrmpPP4fUjJaNYs/5M0Kw8rMOsiaRL7+X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}