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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5c23329807f8f683af098cf966c170e83332f1e939110e3fd060e9433dcd0e' 
  AND token = '/T+FKtQOY/1+k/oCT0/cgNn1T0i4ZpslJBBNSiXlx3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}