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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14042f1b15d8f8ea2fd11f909e599f580dacc8f45b0fecb1199f3a9562d9273c' 
  AND token = 'ObSfAfWp0gUVe/4/VIfa2v1TCT3FHWOqVb6KfVpvyKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}