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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5925a7ab60ea5291ae3f2918381677b07019a8105ed691d5c55d4bbb60b5c735' 
  AND token = '+ForEiB9esbIQMz9fO2E+HXfODEUW7CnRnIVttyAlkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00089

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}