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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6b8fe8c32cd73390843db0f8428a8182790115ad69647580c83d3347b0c21dc' 
  AND token = '+BJnfUwIEwl5Iv764A6m8ot7bITFZfUH3Ft/tBDiVIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}