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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e535c684e91d639fa9dc41547bea52c20521eed6c47a447350f147aa6b1fac' 
  AND token = 'RzqWc4y6Q91qdL3FcbYHfpC/nHvWxS6uTjxmAE/Sq7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}