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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e48e9102c37bbacd02bd5ed55a4202f5e60c48ed5da4db3dbaaf879bbae1b02b' 
  AND token = 'LFoE+pK8LpLT5vuHbXuJSkSoxB+p3/QQc0lprKiWfTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}