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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e36c3fd5d0d335b515a4abbca151c5432edc3bb1c1be5ff5f6e368c79774ed83' 
  AND token = 'l4owYVTZAbVZgKzZu6JyNoh6SP1tNUtiKZzjVQwBkTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}