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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade96860c4e71540ccf5af353d4ca9da3bf3e56dec44d5d04644e0e89892c71f' 
  AND token = 'QGxBc3qHg787DveAueetn0+n/5wymvWFK83otxZv7vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}