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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901f3ea1f307db15794137f4bb5c7d2ce41cee5d252b5683a1db2bdc1bb2cf84' 
  AND token = 'JmVk6YuFMcD+uVR750Ix3e9adATZCdQzR/DVe//engM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}