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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fa80b44b8c606868347cd50e0420bddea4c49fb20c3406f6a0795c402507ecb' 
  AND token = 'ddzEZhIXShz/7XbmPILFTJ3XVhsupZ4Uv4e8M3MviCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}