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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '865aa556701499eed8d950d2004722689c2e2ac9742d5475e96fa38285d6c505' 
  AND token = 'kTm6Zq5caFoQxjVLx2e7sOwjCK8U5rG/iDEO94bNyBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}