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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f97b850c692a17003544406d82d235b81828e915080f071c606f67c5f05df737' 
  AND token = 'RtqyfIzCY28oYzeTAuEwTLoNixPT9srlTq/qIRVIwGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}