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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd55378ceeaca80d88ded83f30f4e80d1197287051dff183671bc67aabf1df72a' 
  AND token = 'zorX1PVEPUk6rK4UlAgAfiDjcJJx4YTDr1i6YVLkBq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}