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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b77ac486111fce3907175f6a368de9736d04e9fa9063e570af876be5ea464ce2' 
  AND token = 'tz33mnxpTdaorV79Y0vuK0hYHNnuBwL6kj9ThNumsww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}