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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9ffa9414debadbf9fd13bdb94de32a0752a866d92b6b5e8c1e489437aa90f2' 
  AND token = 'WhBnl4bU8kRVfyAZFu5zIvLsde0LjJGH6Tyljt1ofFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}