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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ddce5eeb5772b6f23aa49850941004bc56602ca1b3a9098ef7da16e03e7e7be' 
  AND token = 'ncQas/RvNbTSwBFVM1gX5oxkSalQPAEBFxbhoBsH7lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}