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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d45da9899cdfd470b3431803680c2e2d737b49e3115d908e5344bbf9bb2d036' 
  AND token = 'YiNJXJGnfhDu6GWrsDCUoR26QRyJoQxf4ee7E7KQ3ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}