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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f8f12cf339991ffaa4c826b8746386de53ad9f18e4a26e5a39caf434e98467' 
  AND token = 'J5P0ke7z2Ma40NNcM1zA/cCtjoe6+PP7M/cK2ovYkSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}