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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ff385bd3c1cd73e3e6af0670db7f5e33027a0935cff48e8292cdb871834b6e9' 
  AND token = 'GPN0z0gIu01Ze9tyVBDc2+M8ooNRxQyVhN6LYaaPC+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}