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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5f176f7703ee48defc5eaaee4c1cb9e1b9c8a265ef711b9a1b899a99db7de8' 
  AND token = 'jMYUPW8K8tGhqjlo2CnksyKiZL8y1hpLwgKiXoofoc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}