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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd53ca85df7c85d81b3ace7f9970470088aa5bcc5894e820b36bccc246f466be' 
  AND token = 'ZhQSHEoi4bBpZvPN9o3GvqFEf8/vXoXKYnvy1VasFO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}