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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae5ba7ce1f41c5b601aebd44e824426090dfd4b15d962a3df2c592635217d27d' 
  AND token = 'P2n6JFX3PwsSb3kmfl2nxZ+fwdyPa+juN5UIBEmdCnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}