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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9194af4137c2b8e1d14badb7bc59a7209c0f0c1d5e37a002532c51e11feee821' 
  AND token = 'HyBmy1ofX2/f7O+bRrqyKqOoV0iM6/VwWjio6aeUNdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}