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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3b5d71332cd76fb623ee319bc6c39b6666f032c5cbd66a641c75f506833dbb' 
  AND token = 'wrhZBQ4p+EhuO8RHZF8G6uiERGCKHsFqmmkaYyy3G94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}