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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7503d03fdaf7d19d148246b429eb1240b5d73edb2e3a6ba44373ab11a1a89cf3' 
  AND token = 'NbJc7VKhYn/FO4zBKN9sD7LVYbCR4AeNouJkSjdOuPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}