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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7041643f265258078ce41fb907e1e22edbcbe76a168bd37a9d5b251a97a5ae15' 
  AND token = 'UcEx59SUj/GM8BA4Gs23k/kabXYYBZamASjVAKPCM4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}