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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0f1e94a8fa7fc234994ee24177442e50bdd31afd636726af273cbdfb5007ad' 
  AND token = 'CAVkbwAgg1dF8tZQjwvatycuspCcfS+sbBfcQGkaiUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}