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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca20e7a2541b6fdbdb285aa836267d1781c476e71ed638b3bc82646aff8d813' 
  AND token = '4qPdw2SdFYoqZhHqxNbZemwSZqinOEOAN5b9enCmjT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}