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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ddd413cbe6462d53b18b2745a6c6cd4d2aa361798392f9130474a104c77b7b' 
  AND token = '5MQXq0eH5Ruwzo3+M68nsr8qf90vs8eVa8Lj1vEX5Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}