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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d66d5e7ac3bab51cb3c3b7163fcba95eea421dc7d4ef161a18ee7001f6f04b3' 
  AND token = 'qZIGkMT3NyqRe+jB4DLAzExOw4VM0iuzHu5e2b6aq6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}