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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292e15288aca6c2fe21ea451ea7b4bde6ac1dbbb3c5a48fbf6834d8629f07682' 
  AND token = 'H9HdDSUVIx2cjqCjNB2XHnoTSgwj5sH7T07KlHZoS3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}