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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf7f5ded2a4f6a08771439def10437a8030f57a2c798b5efa90ff456f0b230e9' 
  AND token = 'GYrXP2RBOTDP37BlZOJEPWK4nrP9JN0L/TrL1lwOfUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}