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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef861a543cd51fd5b09fb590193e05e121531416e603ede9b9a1159791203824' 
  AND token = 'V+SYJn5ut+dLbyqXrMQPG+sWZ0OErtc5lnyhxKpf9kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}