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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb10820a4e76a7a7c2847d00eacc66cdd99c71b1de722870ba74d9015a46440c' 
  AND token = '9vEyWCi5kg0ddM2Dub/U1IbWaPXPXLsp1x5pMUPMYyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}