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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863af36adef5c1b3b8fbbe353638e972283e4c1361766bd585c605e2bc6654d2' 
  AND token = '4csg2dmjOY3nz9zZEGuBDKY72hoss7hq0YHA5/KdBh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}