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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cabf19cebd6e19965af74b3d2eae0446ca958f01c2177b4c5d1d76dba73c059' 
  AND token = 'D6nj5+HLFNyDeqP/ht7vboo0e9DG+M3kqkgMx1kw8Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}