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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6535e5324f0e6ebb55f5dd5e7cde9aa65d5500b25db1a0323569978bfdb797' 
  AND token = 'J9/plaGIdrT6OPmhmA+SEbJNzPdYj+AHKYkLkWE66xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}