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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b3e72fe0ad30c16b8a1baf3b4b54768772395c38d63a0f633de2ff6452b433d' 
  AND token = 'BiwO7j9eZQThlCksjD/AiCCywYbt+I6wRjuTe4KTR4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}