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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9966db2be9b82bc4782d97b3c2a6dccadaba0369686e2e26312aff0e7d94a77d' 
  AND token = '0KKfqYanLHXQYOA9hXMxb1PYtaLm50m/UkSe0tdiv/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}