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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '394d727da0c09b9e8874dfffa24aa13bdeb26f9eb59f01016c1566c3550b43c6' 
  AND token = 'Aelw7gYfHd6r4xQjkMxQNJ9dbgUBo7id9HHTUz0iRlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}