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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5c3bcd3fc8b791af742cace30f295769b7c2bdb297101d999141af0181e170' 
  AND token = 'ml7itaTauljq018cdX+ENPTptFAj3mjWIbDuaESORgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}