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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5f2ce944315f8814a6565edd36ad3ef9493590de2e4fd860d2186febde70291' 
  AND token = 'MCsKHmlutVO/SLc7Es+Z6OG/yxna2SU8ZZfhxp0SLmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}