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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e362477d010dea6cb9edc3a5829524ba004f5ce76c6ef936528d3277b1e6136' 
  AND token = 'WF9DQgX4/giPQ5x/z7ZdueqvdPymSAQDjLt4G8nSQBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}