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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '750185fbf6f1ee98c4198a60b996eb8fe30e75e2896553795e366741a2921d54' 
  AND token = '9VChgScHaCkUsC+XGfopByPbd2BRCwyb5mGaUb9D6/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}