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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd4c6ac0e3937403329220a304db32e62be19ebf9039e4e6a9135f1a7f1b3eb' 
  AND token = 'I4MGI0G7iY4p678OBu2dDzYQxQzsbDRcI9+Ov1jJIPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}