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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '875b7bfc01c720342e964d310b054e227d4c68239a945f436cbaa4775a240348' 
  AND token = '0+2Cqc6WyA/xI5eNlyhTvpT0L2ntxKxaPmTSDnGKAiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}