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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae00dc936e3078e31306f126dbb6a723326cd189e4209c7fb7255f1b3f3f2984' 
  AND token = 'MPla4gEunUN+uId+bonc32jlH+uHO4bNoH7skJnlzp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}