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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010881bc30f4413fa77cd6a88feac5200aa6de4e5362cec72bcc4aa160166181' 
  AND token = 'EiWUxxbgpgVw13/sly3Ic9e/oi+7kkevN09IHZSDeTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}