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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f48b5a5dd0bf95baa4c027615474cb4ac9ee50497d5d147b8bd557f15881b1ed' 
  AND token = 'R0m1DVd0qn2fwmRZU7hNcDDVvNVHk46/bWiygQC3k7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}